Somewhere in the middle months, a burning ache starts turning up after dinner and gets worse the moment you lie down. It is easy to wave off as one more minor annoyance, especially when there are bigger things to ask about at your next appointment. But heartburn in pregnancy is genuinely common, and most people can improve it a lot with fairly small changes. Here is what drives it, what actually helps, and what is safe to take.
Key takeaways
- Estimates of how common heartburn in pregnancy is vary widely, from about 30% to 80% of pregnant women.
- A 2025 meta-analysis of 21 studies covering 9,497 pregnant participants put the pooled prevalence of reflux symptoms at 40.96%, rising to 55.93% in the third trimester.
- Smaller and slower meals, staying upright after eating, and leaving three hours between dinner and bed do most of the work.
- Antacids and alginates are the usual first-line medicines, and a meta-analysis of 5,618 first-trimester PPI exposures found no significant rise in major malformations.
- Call your midwife or GP if you cannot swallow properly, spit up blood, lose weight, or if symptoms keep waking you at night.
Why heartburn in pregnancy gets worse over the months
Two things happen at once, and neither is your fault. Progesterone relaxes the ring of muscle between your stomach and your food pipe, so acid slips back up more easily. Your growing uterus also pushes your stomach upward, which is why the third trimester is usually the roughest stretch.
Digestion also slows down, so food sits in the stomach longer and brings on bloating, reflux and constipation together. You are more likely to be affected if you had heartburn before you were pregnant, or if you have been pregnant before. It also turns up alongside other third-trimester complaints such as back pain.
The numbers back up how ordinary this is. A 2025 systematic review and meta-analysis pooled 21 studies covering 9,497 pregnant participants and put the prevalence of reflux symptoms at 40.96%. Broken down by trimester, it climbs from 26.12% in the first to 33.40% in the second and 55.93% in the third. Pregnant women in those studies were more than eight times as likely to report reflux symptoms as non-pregnant controls.
What helps day to day
The advice that shows up everywhere is boring and effective. Eat smaller meals more often instead of three big ones, and slow down while you eat. Sitting up straight during and after a meal takes pressure off your stomach. Leaving at least three hours between your last food and bedtime matters more than most people expect.
Where you sleep counts too. Raising the head of your bed by 10cm to 20cm, using blocks or books under the legs, keeps acid from travelling upward overnight. Sleeping on your left side helps as well. Extra pillows do not work, and can make things worse by pressing on your belly.
Cutting back on caffeine and on rich, spicy or fatty food eases symptoms for many people. Some people get quick comfort from yogurt, a glass of milk, or chewing gum, though that is relief rather than a cure.
The evidence behind these habits is thinner than the confidence of the advice suggests. A BMJ Clinical Evidence overview rated the efficacy of six interventions, including acid-suppressing drugs, antacids with or without alginates, raising the head of the bed, and cutting caffeine, fatty food or meal size. Its 2015 update added no new trials at all. Treat the list as sensible clinical practice rather than proven protocol.
If diet and habit changes have not touched your heartburn in pregnancy, that is normal. It means you have finished the first line of care, not that you failed at it.
What is safe to take
Two families of medicine do most of the work. Antacids neutralise the acid already sitting in your stomach, while alginates form a barrier that stops it coming back up. Both are available from a pharmacist, and you should say that you are pregnant, because some antacids are not suitable.
One timing rule catches people out. Do not take antacids within two hours of your folic acid or iron supplement, because they stop those supplements being absorbed properly.
If antacids and alginates are not enough, your GP can prescribe something stronger, usually a proton pump inhibitor such as omeprazole or lansoprazole. The safety picture is reassuring but not perfect. A 2023 meta-analysis pooled 11 studies covering 5,618 first-trimester PPI exposures and found no significant increase in major congenital malformations, with an odds ratio of 1.10 and a confidence interval that crossed 1.0.
The honest caveat is that this evidence comes from observational studies, and there is not enough data to judge each PPI on its own. Cleveland Clinic makes a related point from the other direction: most drug safety trials exclude pregnant women, so more is unknown than anyone would like. Ask your own provider before starting anything, especially in the first trimester.
What to skip
- Do not stack extra pillows to lift your head, use blocks under the bed legs instead.
- Do not eat within three hours of going to bed, or lie down straight after a meal.
- Do not wear anything tight around your waist.
- Do not smoke or drink alcohol, because both make reflux worse and both harm the baby.
Smoking deserves its own line because it works directly on the problem. Chemicals in cigarette smoke relax the ring of muscle at the lower end of your gullet, the same mechanism that lets acid travel back up. It also raises the risk of premature birth and low birthweight, so ask your midwife for help stopping.
Several folk remedies for heartburn in pregnancy sound harmless and are simply unproven. There is no good evidence behind them. Stick with the habits and the pharmacy shelf.
Do not stop a prescribed medicine on your own because you think it is worsening your reflux. Speak to your GP, who may be able to switch you to something else.
Does heartburn mean a hairier baby?
This one has been passed down for generations, and researchers actually tested it in 2006. They asked 64 pregnant women to rate how severe their heartburn was, then had independent coders score newborn hair volume from photographs taken shortly after birth. Severity and hair volume were correlated, at r = 0.40.
The split was striking enough to publish. Of the 28 women with moderate or severe heartburn, 23 had babies with average or above-average hair. Of the 12 women with no heartburn, 10 had babies with less hair than average or none at all. The authors proposed that pregnancy hormones might relax the oesophageal sphincter and influence fetal hair growth at the same time.
Read that as a curiosity, not a forecast. Sixty-four women in a single 2006 study is a small sample, and nobody has repeated it since. Symptom severity was also unrelated to the baby’s sex, so a hairy baby and a girl are not linked either.
When to get medical help
Routine reflux is uncomfortable, not dangerous, and the list of things that should prompt a call is short. See your midwife or GP if lifestyle changes and pharmacy medicines are not controlling your symptoms, or if heartburn is happening most days.
NHS guidance also lists difficulty swallowing, a hoarse voice, a cough that keeps coming back, swollen glands on each side of your neck, unexplained weight loss, and pain or swelling in your stomach as reasons to get checked. Cleveland Clinic adds heartburn that wakes you at night, spitting up blood, and black stool.
One warning is worth knowing by heart. Heartburn can feel like a heart attack. If you have never had it before and you are having chest pain, contact your provider or go to the nearest emergency room instead of waiting to see whether it settles. More symptom guides are collected in the pregnancy health archive.
How Utun can help
Utun is our own pregnancy companion app, built for exactly this stretch of pregnancy. It gives you development information with daily guidance matched to how far along you are, plus a weight log, a kick counter, a contraction timer, a mood journal, a hospital bag checklist and trimester to-do lists. If you want one place to keep track of symptoms like these, it is on Google Play and listed with our other apps on the products page.
Is heartburn in pregnancy a sign of a girl?
No. In the 2006 study that measured it, symptom severity was unrelated to fetal sex, along with parity, age and weight. The sex prediction belongs with the other old wives’ tales about carrying high or craving sweets.
Can I take omeprazole while pregnant?
Possibly, but only with a doctor’s agreement. NHS guidance says a GP may prescribe a proton pump inhibitor if antacids and alginates have not worked. The pooled evidence from 5,618 first-trimester exposures found no significant increase in major malformations, but it came from observational studies, so it is not a green light to self-prescribe.
Why is heartburn worse at night?
Lying flat takes gravity out of the equation and lets acid pool in your food pipe. Eating close to bedtime makes it worse. Raising the head of your bed and leaving three hours after eating are the two changes that help most.
Does it go away after birth?
For most people, yes. Cleveland Clinic notes that heartburn in pregnancy usually settles once the baby is born, so if you never had reflux before pregnancy there is a good chance you will not have it afterwards.
This article is educational and is not medical advice. Talk to your midwife, GP or another qualified healthcare provider about your own symptoms, and before taking any medicine during pregnancy.
Featured image: “Glass of milk” by Santeri Viinamäki, CC BY-SA 4.0, via Wikimedia Commons.
Sources
- NHS. Indigestion and heartburn in pregnancy. https://www.nhs.uk/pregnancy/common-symptoms/indigestion-and-heartburn/
- NHS. Heartburn and acid reflux. https://www.nhs.uk/conditions/heartburn-and-acid-reflux/
- Cleveland Clinic. Heartburn During Pregnancy: Causes & Treatment. https://my.clevelandclinic.org/health/diseases/12011-heartburn-during-pregnancy
- Khurmatullina AR, Andreev DN, Maev IV, et al. Global prevalence and risk of gastroesophageal reflux disease symptoms in pregnancy: a systematic review and meta-analysis. BMC Pregnancy Childbirth. 2025. https://pubmed.ncbi.nlm.nih.gov/41366751/
- Peron A, Ripoche E, Picot C, et al. Use of proton pump inhibitors during pregnancy: a systematic review and meta-analysis of congenital malformations. Reprod Toxicol. 2023. https://pubmed.ncbi.nlm.nih.gov/37269915/
- Vazquez JC. Heartburn in pregnancy. BMJ Clinical Evidence. 2015. https://pubmed.ncbi.nlm.nih.gov/26348641/
- Costigan KA, Sipsma HL, DiPietro JA. Pregnancy folklore revisited: the case of heartburn and hair. Birth. 2006;33(4):311-314. https://pubmed.ncbi.nlm.nih.gov/17150070/
